Clinical Trials
| Title | Description |
|---|---|
| S1802 |
NCT03678025 Phase III Randomized Trial of Standard Systemic Therapy (SST) versus Standard Systemic Therapy Plus Definitive Treatment (Surgery or Radiation) of the Primary Tumor in Metastatic Prostate Cancer |
| 1606636273 – NRG-GY006 |
NCT02466971 A Randomized Phase II Trial of Radiation Therapy and Cisplatin Alone or in Combination with Intravenous Triapine in Women with Newly Diagnosed Bulky Stage IB2, Stage II, IIIB, or IVA Cancer of the Uterine Cervix or Stage II-IVA Vaginal Cancer |
| NRG-GU002 |
NCT03070886: Phase II-III trial of adjuvant radiotherapy and androgen deprivation following radical prostatectomy with or without adjuvant Docetaxel |
| NRG-GU007 |
NCT04037254: Randomized Phase II Trial of Niraparib with Standard Combination Radiotherapy and Androgen Deprivation Therapy (ADT) in High Risk Prostate Cancer (With Initial Phase I) |
| Comppare |
NCT03561220 A Prospective Comparative Study of Outcomes with Proton and Photon Radiation in Prostate Cancer |
Shona T. Dougherty, MB, ChB, PhD| Title | Description |
|---|---|
| Astrazeneca/ Pacifica 4 |
NCT03833154 A Phase III, Randomised, Double-blind, Placebo-controlled, Multi-centre, International Study of Durvalumab following stereotactic body radiation therapy (SBRT) for the treatment of Patients with Stage I/II Non Small Cell Lung Cancer |
| LU005 |
NCT03811002 Limited Stage Small Cell Lung Cancer (LS-SCLC): A Phase II/III Randomized Study of Chemoradiation versus Chemoradiation Plus Atezolizumab |
| EA6174 |
NCT03712605 A Phase III Randomized Trial Comparing Adjuvant MK-3475 (Pembrolizumab) to Standard of Care Observation in Completely Resected Merkel Cell Carcinoma |
| NRG-LU002 |
NCT03137771: Maintenance Systemic Therapy Versus Consolidative Stereotactic Body Radiation Therapy (SBRT) Plus Maintenance Systemic Therapy for Limited Metastatic Non-Small Cell Lung Cancer (NSCLC): A Randomized Phase II/III Trial |
| S1827 |
NCT04155034 MRI Brain Surveillance Alone Versus MRI Surveillance and Prophylactic Cranial Irradiation (PCI): A Randomized Phase III Trial in Small-Cell Lung Cancer (MAVERICK) |
| ANAM 17-21 Cachexia |
NCT03743064 A Phase 3, randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy and safety of anamorelin HCl for the treatment of malignancy associated weight loss and anorexia in adult patients with advanced non-small cell lung cancer (NSCLC). |
Charles C. Hsu, MD, PhD| Title | Description |
|---|---|
| RTOG 3507 |
NCT03546582 A Randomized Phase II Study of Pembrolizumab (Keytruda) plus Stereotactic Re-irradiation versus SBRT Alone for Locoregionally Recurrent or Second Primary Head and Neck Carcinoma |
| 1805527255 |
NCT03509012 Phase I Multicenter Study of Immunotherapy in Combination with Chemoradiation in Patients with Advanced Solid Tumors (CLOVER) |
| A091802 |
NCT03944941 Phase II Randomized Trial of Avelumab Plus Cetuximab Versus Avelumab Alone in Advanced Cutaneous Squamous Cell Carcinoma of the Skin (cSCC) |
| NRG-HN005 |
NCT03952585: A Randomized Phase II/III Trial of De-Intensified Radiation Therapy for Patients with Early-Stage, P16-Positive, Non-Smoking Associated Oropharyngeal Cancer |
| RTOG-1008 |
NCT01220583: A Randomized Phase II/Phase III Study of Adjuvant Concurrent Radiation and Chemotherapy Versus Radiation Alone in Resected High-Risk Malignant Salivary Gland Tumors |
| EA3132 |
NCT02734537 Phase II Randomized Trial of Adjuvant Radiotherapy with or Without Cisplatin for p53 Mutated, Surgically Resected Squamous Cell Carcinoma of the Head and Neck (SCCHN) |
| RTOG 3507 |
NCT03546582 A Randomized Phase II Study of Pembrolizumab (Keytruda) plus Stereotactic Re-irradiation versus SBRT Alone for Locoregionally Recurrent or Second Primary Head and Neck Carcinoma |
| RTOG 3507 |
NCT03546582 A Randomized Phase II Study of Pembrolizumab (Keytruda) plus Stereotactic Re-irradiation versus SBRT Alone for Locoregionally Recurrent or Second Primary Head and Neck Carcinoma |
Jared Robbins, MD| Title | Description |
|---|---|
| CCTG CE.7 |
NCT03550391: Phase III Trial of Stereotactic Radiosurgery Compared with Whole Brain Radiotherapy (WBRT) for 5-15 Brain Metastases |
| NRG-BN003 |
NCT03180268: Phase III Trial of Observation Versus Irradiation for a Gross Totally Resected Grade II Meningioma |
| EAF151 |
NCT03115333 Change in Relative Cerebral Blood Volume as a Biomarker for Early Response to Bevacizumab in Patients with Recurrent Glioblastoma |
| A071801 |
NCT04114981 Phase III Trial of Post-Surgical Single Fraction Stereotactic Radiosurgery (SRS) Compared with Fractionated SRS (FSRS)for Resected Metastatic Brain Disease |
Baldassarre Stea, MD, PhD, FASTRO