Baldassarre Stea, MD, PhD, FASTRO

Baldassarre Stea, MD, PhD, FASTRO

Deparment Head

Residency Director 

Professor

Contact Information

Office Location: 
3838 N Campbell Ave., BLDG 2
Phone Number: 
(520) 694-7236
Fax: 
(520) 694-0197

Background

Dr. Stea earned his doctorate in biochemistry at UCLA, followed by a medical degree from George Washington University, Washington, D.C. He received his residency training in radiation oncology at the National Cancer Institute in Bethesda, MD. Since his appointment with The University of Arizona Cancer Center, Dr. Stea has served as Director of the Radiation Oncology Residency Training Program from 1995-1998, and has been Medical Director of the Department since 1997. Dr. Stea has been head professor of the Department of Radiation Oncology since 2003.

Dr. Stea is board-certified in radiation oncology, and specializes in the treatment of malignant and benign brain tumors using stereotactic radiosurgery (SRS). He developed the stereotactic radiosurgery program at the University of Arizona, and has more than 20 years of experience in the field.

Dr. Stea's research is focused on the development of novel radiation enhancers and radiosensitizing drugs for primary and secondary brain tumors. His clinical practice focuses on treatment of malignant brain tumors and pediatric cancers, including total body irradiation (TBI). He received the UMC “Patient's Choice Award" for outstanding communication and excellence in patient care 1994, 1995 and 1998, and has been listed among The Best Doctors in America since 1996.

Professional Affiliations: 
  • Courtesy Consultant, Northwest Hospital, Tucson, Ariz.
  • Courtesy Staff, Tucson Medical Center, Tucson, Ariz.
  • Consultant in Radiation Oncology, Veterans Administration Medical Center, Tucson, Ariz.
  • Medical Staff Fellow, Radiation Oncology Branch, National Cancer Institute, Bethesda, Md.
  • Intern in Medicine, George Washington University
  • Summer Research Fellow, George Washington University, Cancer Research Laboratory
  • Summer Research Fellow, University of Bari (Italy), Department of Biological Chemistry
  • NIH/NRSA Predoctoral Trainee, UCLA, Department of Chemistry
  • Postdoctoral Fellow, UCLA, Department of Chemistry
  • Teaching Fellow, UCLA, Department of Chemistry
  • Teaching Associate, UCLA, Department of Chemistry
  • Research Associate, UCLA, Department of Chemistry
  • Teaching Assistant, UCLA, Department of Chemistry
  • Research Assistant, UCLA, Department of Surgery/Oncology
Honors: 
  • Admitted to the Honors Program, UCLA (1974)
  • Graduated cum laude, UCLA (1974)
  • NIH/NRSA Predoctoral Trainingship, UCLA
  • Recipient of the Phi Beta Kappa Alumni Association Scholarship
  • Travel Award to the 1st Pathobiology of Cancer Workshop (Keystone, CO)
  • Research Grant Award from the Italian National Research Council
  • ALPHA OMEGA ALPHA Medical Society
  • The Hubon W. Lawson Award for Most Outstanding Student in OB/GYN
  • The Howard K. Kane - A.F.A. King Obstetrical Honor Society
  • American Cancer Society - Clinical Oncology Career Development Award
  • Travel Grant Award to Paris, France for the 17th International Congress of Radiology; Office of International Programs, University of Arizona
  • Recipient of ASTRO Award to attend the European Society for Therapeutic Radiology and Oncology (ESTRO) meeting in Montecatini, Italy
  • Travel Grant Award to from the Office of International Programs to attend the First International Symposium on Neuro-Radio-Surgery in Vienna, Austria
  • "Patient's Choice Award" from UMC for Outstanding Communication and Quality Care
  • Travel Grant Award from the Office of International Programs to attend the VII International Congress on Hyperthermic Oncology in Rome, Italy
  • Listed in the "The Best Doctors in America: Pacific Region," 1996-1997 Edition
  • Strathmore's "Who's Who," 2001-2002 Registry
  • Listed in "The Best Doctor's in America," 1998-2011
  • Recipient of the first annual Physician Award from the UMC Board of Directors
  • Faculty Teaching Award - Longitudinal Clinical Curriculum preceptor of the year (2006)

Clinical

Board Certifications: 

Diplomate of the National Board of Medical Examiners Diplomate of the American Board of Radiology (Radiation Oncology)

Clinical Practice Sites: 
The University of Arizona Cancer Center - Orange Grove
Radiation Oncology
The University of Arizona Medical Center - University Campus

Education

Doctorate: 
UCLA, Los Angeles, Calif.
Medical School: 
George Washington University, Washington, D.C.
Master's Degree: 
UCLA, Los Angeles, Calif.
Undergraduate School: 
UCLA, Los Angeles, Calif.

Research

Selected Publications: 
 

 Halpern, R.M., Halpern, B.C., Stea, B., Dunlap, A., Conklin, K., Clark, B., Ashe, H., Sperling, L., Halpern, J.A., Hardy, D., and Smith, R.A.  Pterion-6-aldehyde, a Cancer Cell Catabolite: Identification and Application in Diagnosis and Treatment of Human Cancer.  Proc. Natl. Acad. Sci. USA 74:587-591, 1977.

 

Stea, B., Backlund, P.S., Jr., Berkey, P.B., Cho, A.K., Halpern, B.C., Halpern, R.M., and Smith, R.A.  Folate and Pterin Metabolism by Cancer Cells in Culture.  Cancer Res. 38:2378-2384, 1978.


 Stea, B., Halpern, R.M., and Smith, R.A.  Separation of Unconjugated Pteridines by High-pressure Cation-exchange Liquid Chromatography.  J. Chromatog.  168:385-393, 1979.

 

Stea, B., Halpern, R.M., Halpern, B.C., and Smith, R.A.  Quantitative Determination of Pterins in Biological Fluids by High-pressure Liquid Chromatography.  J. Chromatogr. 188:363-375, 1980.

 

Stea, B., Halpern, R.M., Halpern, B.C., and Smith, R.A.  Urinary Excretion Levels of Unconjugated Pterins in Cancer Patients and Normal Individuals.  Clin. Chim. Acta. 113:231-242, 1981.

 

Stea, B., and Smith, R.A.  Urinary Unconjugated Pteridines: General Considerations.  Survey of Immunologic Research.  1:357, 1982.

 

Stea, B., Kinsella, T., Triche, T., Horvath, K., Glatstein, E. and Miser, J.  Treatment of Pelvic Sarcomas in Adolescents and Young Adults with Intensive Combined Modality Therapy.  Int. J. Radiat. Oncol. Biol. Phys. 13:1797-1805, 1987.

 

Stea, B., Cavazzana, A. and Kinsella, T.J.  Small Cell Osteosarcoma: Correlation of In Vitro and Clinical Radiation Response.  Int. J. Radiat. Oncol. Biol. Phys. 15:1233-1238, 1988.

 

Hynynen, K., Shimm, D., Anhalt, D., Stea, B., Fosmire, H., Cassady, J.R., and Roemer, R.B.  Temperature Distributions During Clinical Scanned Focussed Ultrasound Hyperthermia Treatments.  Int. J. Hyperthermia 6:891-908, 1990.

 

Cress, A.E., Kurath, K.M. and Stea, B.  The Cross-Linking of Nuclear Proteins to DNA Using Ionizing Radiation.  J. Cancer Research and Clinical Oncology, 116:324-330, 1990.

 

Lulu, B.A., Lutz, W., Cetas, T. and Stea, B.  Treatment Planning of Template Guided Stereotaxic Brain Implants.  Int. J. Radiat. Oncol. Biol. Phys. 18:951-955, 1990.

 

McBride, H., Stea, B., Hill, A. and Trent, J.   Possible Relationship between Chromosome Alterations and Radiosensitivity in Human Malignant Melanoma.  Int. J. Radiat. Oncol. Biol. Phys.  19:349-355, 1990.

 

Stea, B., Cetas, T.C., Cassady, J.R., Guthkelch, A.N., Iacono, R., Lulu, B., Lutz, W., Obbens, E., Rossman, K., Seeger, J., Shetter, A. and Shimm, D.S.    Interstitial Thermoradiotherapy of Brain Tumors: Preliminary Results of a Phase I Clinical Trial.  Int. J. Radiat. Oncol. Biol. Phys. 19:1463-1471, 1990.

 

Guthkelch, A.N., Carter, L.P., Cassady, J.R.,, Hynynen, K., Iacono, R.P., Johnson, P.C., Obbens, E., Roemer, R., Seeger, J.F., Shimm, D.S. and Stea, B.   Treatment of Malignant Brain Tumors with Focused Ultrasound Hyperthermia and Radiation: Results of a Phase I Trial.  J. Neuro-Oncology 10:271-284, 1991.

 

John M. Buatti, Baldassarre Stea, David E. Stringer, Eugene W. Gerner. Polyamine modulation of c-myc expression and its effects on radioresponses of human glioblastoma cells (astro fellowship International Journal of Radiation Oncology Biology Physics 01/1991; 21:126-126. DOI:10.1016/0360-3016(91)90454-C

 

Harari, P.M., Hynynen, K.H., Roemer, R.B., Anhalt, D.P., Shimm, D.S., Stea, B. and Cassady, J.R.  Scanned Focused Ultrasound: Clinical Response Evaluation.  Int. J. Radiat. Oncol. Biol. Phys. 21:831-840, 1991.

 

Stea, B., Kittelson, J., Cassady, J.R., Hamilton, A., Guthkelch, N., Lulu, B., Obbens, E., Rossman, K., Shapiro, W., Shetter, A. and Cetas, T.  Treatment of Malignant Gliomas With Interstitial Irradiation and Hyperthermia.  Int. J. Radiat. Oncol. Biol. Phys. 24:657-667, 1992.

 

Fosmire, H., Hynynen, K., Drach, G., Stea, B., Swift P. and Cassady, J.R.   Feasibility and Toxicity of Transrectal Ultrasound Hyperthermia in the Treatment of Locally Advanced Adenocarcinoma of the Prostate.  Int. J. Radiat. Oncol. Biol. Phys. 26:253-259, 1993.

 

Stea, B., Buatti, J., Stringer, D. and Gerner, E.W.  Inhibition of Polyamine Synthesis Suppresses Growth and Gamma-Ray-Induced Sublethal and Potentially Lethal Damage Recovery in Human Tumor Cells in Culture.  Radiat. Oncol. Investigation 1:41-49, 1993.

 

Mack , C., Stea, B., Kittelson, J., Shimm, D., Sneed, P., Phillips, T., Swift, P., Luk, K., Stauffer, P., Chan, K.,  Steeves, R., Cassady, J.R. and Cetas, T.  Interstitial Thermoradiotherapy with Ferromagnetic Implants for Locally Advanced and Recurrent Neoplasms.  Int. J. Radiat. Oncol. Biol. Phys. 27:109-115, 1993.

 

Stea, B., Rossman, K., Kittelson, J., Lulu, B., Shetter, A., Cassady, J.R. and Hamilton, A.   A Comparison of Survival Between Radiosurgery and Stereotactic Implants for Malignant Astrocytomas.  Acta Neurochirurgica 62:47-54, 1994.

 

Stea, B., Rossman, K., Kittelson, J., Shetter, A., Hamilton, A. and Cassady, J.R.  Interstitial Irradiation Versus Interstitial Thermoradiotherapy for Supratentorial Malignant Gliomas: A Comparative Survival Analysis.    Int. J. Radiat. Oncol. Biol. Phys. 30:591-600, 1994.

 

Leigh, B., Stea, B., Cassady, J.R., Kittelson, J. and Cetas, T.  Clinical Hyperthermia with a New Device: The Current Sheet Applicator.  Int. J. Radiat. Oncol. Biol. Phys. 30:945-951, 1994.

 

Cheng, C.W., Das, I.J. and Stea, B.   Three-dimensional Treatment Planning of the Breast: Requirement of the Number of CT Slices and Evaluation of Treatment Planning Systems.  Int. J. Radiat. Oncol. Biol. Phys. 30:183-195, 1994

 

Gannett D, Woolridge D, Stea B, Hamilton A, Gerner E.W. Hypusine as a potential prognostic marker in glial derived brain tumors. Int. J. of Radiat.  Oncol. Biol.Phys. 32(971):202-202, 1994.

 

Hamilton, A., Lulu, B., Stea, B., and Cassady, J.R.  A Technique Employing Silastic Anchoring Sheets for Securing Multiple, Percutaneous Catheters for Stereotactic Interstitial Brachytherapy for Intracranial Tumors.  Endocur. Hyperth. Oncol. 10:157-160, 1994.

 

Hamilton, A., Lulu, B., Fosmire, H., Stea, B. and Cassady, J.R.   Preliminary Clinical Experience with Linear Accelerator-based Spinal Stereotactic Radiosurgery.  Neurosurgery 36:311-319, 1995.

 

Hamilton, A., Stea, B., Cheng, C.W., and Lulu, B.   The Use of Gold Foil Wrapping for Radiation Protection for the Spinal Cord for Recurrent Tumor Therapy.  Int. J. Radiat. Oncol. Biol. Phys. 32:507-511, 1995.

 

Anderson, J.M., Cassady, J.R., Shimm, D.S., and Stea, B.  Vulvar Carcinoma.  Int. J. Radiat. Oncol. Biol. Phys. 32:1351-1357, 1995.

 

Gannett, D., Stea, B. ,  and  Shimm, D.  Interstitial Thermoradiotherapy for Locally Advanced and Recurrent Neoplasms of the Head and Neck.  Endocurietherapy 11:143-153, 1995.

 

Warneke, J., Grossklaus, D., Davis, J., Stea, B., Poole, L., Bebb, G., Taylor, C., Hastings, R., and Villar, H.  Influence of Local Treatment on the Recurrence Rate in DCIS.  Journal of the Am. College of Surgery.  180:683-688, 1995.

 

Gannett, D., Stea, B., Lulu, B., Adair, T., Verdi, C. , and Hamilton, A.  Stereotactic Radiosurgery as an Adjunct to Surgery and External Beam Radiotherapy in the Treatment of Patients with Malignant Gliomas.  Int. J. Radiat. Oncol. Biol. Phys. 33:461-468, 1995.

 

Warneke, J., Berger, R., Villar, H., and Stea, B.    Lumpectomy and Radiation Treatment for Invasive Lobular Carcinoma of the Breast.    Am. J. of Surgery 172 (5): 496, 1996.

 

Gannett, D., Hill, D., Hamilton, A. , and Stea, B.   Paclitaxel as a Radiosensitizer Combined with Fractionated Stereotactic Radiotherapy in the Treatment of Recurrent Medulloblastoma.   Am. J. Clin. Onc.  20(3):233-236, 1997.

 

Woo, C., Stea, B., Lulu, B., and  Hamilton, A.  The Use of Stereotactic Radiosurgical Boost in the Treatment of Medulloblastomas.  Int. J. Radiat. Onc. Biol. Phys.  37(4):761-764, 1997.

 

Dee-Donaldson, L., Witte, M.H., Bernas, M., Witte, C.L., Way, D., Stea, B.  Refinement of a Rodent Model of Peripheral Lymphedema.  Lymphology 32:111-117, 1999.

 

Istvan Takacs, AJ Hamilton, Bruce Lulu, Helen Fosmire, Patrick Johnson, Baldassarre Stea, ... Frame Based Stereotactic Spinal Radiosurgery: Experience from the First 19 Patients Treated Stereotactic and Functional Neurosurgery 02/1999; 73(1-4):69. DOI:10.1159/000029755

 

Anderson, J., Stea, B., Hallum, A., Rogoff, E., and Childers, J.  High-Dose-Rate Postoperative Vaginal Cuff Irradiation Alone for Stage 1B and 1C Endometrial Cancer.  Int. J. Radiat. Onc. Biol. Phys. 46(2):417-425, 2000.

 

Algan, Ö., Fosmire, H., Hynynen, K., Dalkin, B., Cui, H., Drach, G., Stea, B.,  and Cassidy, R.  External Beam Radiotherapy and Hyperthermia in Treatment of Patients with Locally Advanced Prostate Carcinoma: Results of Long Term Follow-up.  Cancer 89(2):399-403, 2000.

 Thomas, R., Stea, B. Radiation Recall Dermatitis from High-Dose Interferon Alpha-2b. J. Clinical Oncology 20(1):355-357, 2002

 

 Kriederman, B., Myloyde, T., Bernas, M., Lee-Donaldson, L., Preciado S., Lynch, M., Stea, B., Summers, P, Witte, C., Witte, M. Limb Volume Reduction After Physical Treatment by Compression and/or Massage in a Rodent Model of Peripheral Lymphedema. Lymphology 35, 23-27, 2002

 

Briggs, J.H., Algan, O., Stea, B.  Primary T-Cell Lymphoma of the Breast: A Case Report.  Cancer Invest.  2003;21 (1):68-72.

 

Shaw,E.., Scott,C., Suh, J.Kadish, S., Stea,B..,Hackman, J., Pearlman,A., Murray, K., Gaspar, L., Mehta, M, Curran, W., and Gerber,M. RSR13 Plus Cranial Radiation Therapy in Patients with Brain Metastases: Comparison with the RTOG Recursive Partitioning Analysis Brain Metastases Data Base. J. Clin. Oncol. 21, 2364-2371, 2003.

 

Stea, B., Falsey, R., Kislin, K., Patel, J., Glanzberg, H., Carey, S., Meuillet, E. J., Martinez, J.D. Growth Inhibition and Radiosensitization of Glioblastoma Multiforme by the EGFR-Receptor Tyrosine Kinase Inhibitor ZD1839 (Iressa). Cancer Letters 202,43-51, 2003.

 

Choy H, Nabid A, Stea B, Scott C, Roa W, Kleinberg L, Ayoub J, Smith C, Souhami L, Hamburg S, Spanos W, Kreisman H, Boyd AP, Cagnoni PJ, Curran WJ.  Phase II Multicenter Study of Induction Chemotherapy Followed by Concurrent Efaproxiral (RSR13) and Thoracic Radiotherapy for Patients with Locally Advanced Non-Small Cell Lung Cancer.  J Clin Oncol 23, 5918-28, 2005.

 

Suh J,  Stea B,  Nabid A,  Kresl J,  Fortin A, Mercier JP, Senzer N, Chang E, Boyd AP, Cagnoni PJ, Shaw E.  Results from a phase III study evaluating Efaproxiral as an adjunct to whole brain radiation therapy for the treatment of patients with brain metastases. J Clin Oncol. 24(1):106-14. 2006.

 

Gabayan AJ,  Green, SB,  Sanan, A,  Jenrette J,  Schultz C, Papagikos M, Tatter SP, Patel A,       Amin A,  Tonnesen GL, Lustig R, Bastin KT, Watson G, Burri S, Stea B.   GliaSite radiotherapy    system for treatment of recurrent gliomas.  Neurosurgery 2006; 58:701-709.

 

Stea B,  Suh JH, Boyd AP, Cagnoni PJ, Shaw E.  Whole brain radiation therapy with or without Efaproxiral for the treatment of brain metastases: determinants of response and its prognostic value for subsequent survival. Int J Radiat Oncol Biol Phys. 2006 Mar 15;64 (4):1023-30.

 

B. Stea, E. Shaw, T. Pintér, J. Hackman, M. Craig, J. May, R.P. Steffen, and J.H. Suh   Efaproxiral Red Blood Cell Concentration Predicts Efficacy in Patients with Brain Metastases, British J Cancer (2006) 94, 1777-1784.

 

Welsh J, Gabayan A, Green SB, Lustig R, Burri, S, Kwong E, Stea B. GliaSite Radiotherapy Boost as part of the    initial treatment of Glioblastoma Multiforme: a retrospective multi-institutional pilot study. Inter J Rad Oncol Biol Phys 68 (1), 159-165, 2007.

 

Pawar S, Dougherty S, Pennington ME, Demetriuou, MC Stea B, Dorr RT, Cress AE; |*alpha*|6 Integrin Cleavage:  Sensitizing Human Prostate Cancer to Ionizing Radiation. Int J Radiat Biol. 2007 Nov; 83(11):761-767.

 

Scott, J. Suh, J, Stea, B, Nabid, A, Hackman, J.   Improved Survival, Quality of Life, and Quality-Adjusted Survival in Breast Cancer Patients Treated with Efaproxiral (Efaproxyn™) Plus Whole Brain Radiation Therapy for Brain Metastases; American Journal of Clinical Oncology;30(6):580-7, 2007.

 

Persky D, Unger J, Spier CM, Stea B, Maloney DG, LeBlanc M, Rimsza LM, Fisher RI, Miller TP; Phase II study of rituximab plus three cycles of CHOP and involved-field radiotherapy for patients with limited-stage aggressive B-cell lymphoma: Southwest Oncology Group study 0014.  J Clin Oncol. 2008 May 10, 26(14):2258-63.

 

Watchman, C, Hamilton, R and Stea B. Patient positioning using implanted gold markers with the Novalis Body System in the Thoracic Spine. Neurosurgery 62, A62-A68, 2008.

 

Chino K, Silvain D Grace A, Stubbs, J, Stea, B. Feasibility and safety of outpatient brachytherapy in 37 patients with brain tumors using the GliaSite Radiation Therapy System. Med Phys 2008 Jul;35(7):3383-8.

 

 Chino, K., Tanyi JA and Stea, B. Stereotactic radiotherapy for unilateral orbital lymphoma and orbital pseudo-tumors: a planning study.  Med Dosim. 2009 Spring; 34(1):57-62. Epub 2008 Mar 28.

 

Welsh J, R. Ellsworth, R Kumar, M Berens, J Martinez, K Fjerstad, R. Nagle, B. Stea. Rad51  Protein Expression and Survival in Patients with Glioblastoma Multiforme (GBM). Int J Rad Onc Biol Phys, 74 (4): 1251-1255, 2009.

 

Welsh J, Mahadevan D, Bearss D, Cooke L, Dougherty G, Stea B; A c-Met receptor Thyrosine  Kinase Inhibitor Radiosensitizes Glioblastoma. Radiation  Oncology 4:69, 2009.

 

Chi A, Liao Z, Nguyen NP, Xu J, Stea B, Komaki R; Systematic review of the patterns of failure following stereotactic body radiation therapy in early-stage non small cell lung cancer: Clinical implications. Radiotherapy and Oncology 2010 Jan 94(1): 1-11. Review.

 

Hsieh D., Hsieh A, Ellsworth R, Stea B; IGFBP2 promotes glioma tumor stem cell expansion and survival.  Biochem Biophys Res Commun. 2010 Jun 25; 397 (2):367-372.

 

Badruddoja MA, Elquza E, Welsh J, Cooke L, Sanan A, Stea B, Mahadevan, D; The development of PDGF Receptor Inhibitors for the Treatment of Gliomas: A Review. Lett in Drug Design Discovery. 2010; 7(4): 290-299.

 

Daley SK, Michael J Bernas  MJ, Stea B, Bracamonte E, McKenna M, Stejskal A, Hirleman E, and Marlys H Witte. Radioprotection from radiation induced lymphedema without tumor protection. Lymphology 43 (2); 48-58, 2010.

 

Chelliah D, Mensah Sarfo-Poku C, Stea BD, Gardetto J, Zumwalt J. Medulloblastoma with extensive nodularity undergoing post-therapeutic maturation to a gangliocytoma: a case report and literature review. Pediatr Neurosurg. 2010; 46(5):381-4. Epub 2011 Mar 9.

 

Stea B, Hazard JL, Gonzalez JV and Hamilton JR. The Role of Radiation Therapy in the Control of Locoregional and Metastatic Cancer J. Surg Oncol. 2011 May 1; 103 (6):627-638. Review.

 

Stea B and Gordon J. Clinically Relevant Biomarkers in Targeted Radiotherapy. Clin Exp Metastasis. 2012 Oct; 29 (7):853-60. doi: 10.1007/s10585-012-9523-z. Epub 2012 Aug 11. PMID: 22886523 [PubMed - indexed for MEDLINE].

 

Welsh, JW, Komaki R, Amini A, Munsell M, Unger W, Allen PK, Chang JY, Wefel J, McGovern S, Garland LL, Chen SS, Holt J, Liao Z, Brown P, Sulman E, Heymach JV, Kim ES, and Stea B; Phase II Trial of Erlotinib plus Concurrent Whole-Brain Radiation Therapy for Patients with Brain Metastases from Non-Small Cell Lung Cancer. J Clin Oncol. 2013 Mar 1;31(7):895-902. doi: 10.1200/JCO.2011.40.1174. Epub 2013 Jan 22. PMID: 23341526

  

Persky DO, Miller TP, Unger JM, Spier CM, Puvvada S, Stea B, Press OW, Constine LS, Barton KP, Friedberg JW, LeBlanc M, Fisher RI; Ibritumomab Tiuxetan Consolidation After 3 Cycles of CHOP Plus Radiotherapy For High Risk Limited Stage Aggressive B-cell Lymphoma; Blood. 2015 Jan 8;125(2):236-41. doi: 10.1182/blood-2014-06-584623. Epub 2014 Nov 13. PMID:25395425

 

Vonk D, Kim Y, Javid C, Gordon, J, Stea, B; Prescribing to tumor apex in episcleral plaque iodine-125 brachytherapy for medium-sized choroidal melanoma: A single-institutional retrospective Brachytherapy. 2015 Jun 5. pii: S1538-4721(15)00472-9. doi: 10.1016/j.brachy.2015.05.002. [Epub ahead of print] PMID:26051804

 

Goyal U, Kim Y, Arif HT, Witte R, Stea, B; A Pilot Study of Ultrasound-guided Electronic Brachytherapy for Skin Cancer. J Contemp Brachytherapy. 2015 Oct; 7(5):374-80. doi: 10.5114/jcb.2015.55538.Epub2015 Oct 30. PMID: 26622244 PMCID: PMC4663218 DOI: 10.5114/jcb.2015.55538  

 

Skrepnik T, Gottesman, S, Stea B; Long term benefit of electron beam radiotherapy in the treatment of Scleredema of Buschke: Advances in Radiation Oncology. 2016 Volume 1, Issue 1, Pages 21–25.  DOI: http://dx.doi.org/10.1016/j.adro.2015.11.002

 

Ashby LS, Smith KA, Stea B. Gliadel wafer implantation combined with standard radiotherapy and concurrent followed by adjuvant temozolomide for treatment of newly diagnosed high-grade glioma: A systematic literature review.World J Surg Oncol. 2016 Aug 24; 4(1):225. doi: 10.1186/s12957-016-0975-5. Review. PMID: 27557526 

 

Frankl J, Grotepas C, Stea, B, Lemole G, Chiu A, and Khan R. Chordoma    Dedifferentiation after Proton Beam Therapy. Journal of Medical Case Reports (2016) 10:280 DOI 10.1186/s13256-016-1076-32016

 

Slane BG, Goyal U, Grow JL, Morrison C, Hullet, CR, Gordon J, Sanan, A, Stea, B. Radiotherapeutic    management of vestibular schwannomas using size and location-adapted fractionation regimens to maximize the therapeutic ratio. Pract Radiat Oncol. 2017 May - Jun;7(3):e233-e241. doi: 10.1016/j.prro.2016.10.016. Epub 2016 Oct 28 

 

Goyal U, Pan J, Cui H, Stea B.  Does ultrasound measurement improve the accuracy of electronic brachytherapy in the treatment of superficial non-melanomatous skin cancer? J Contemp Brachytherapy 2017; 9, 1: 14–19 DOI: https://doi.org/10.5114/jcb.2017.65476

 

Skrepnik T, Sundararajan S, Cui H, Stea, B. Improved time to treatment progression in the brain in patients with melanoma brain metastases treated with concurrent delivery of radiosurgery and ipilimumab. Onco-immunology; Jan 2017 http://dx.doi.org/10.1080/2162402X.2017.1283461

 

Nael, K, Germano I, Lemole M and Stea B. Multiparametric MRI for Differentiation of Radiation Necrosis from Recurrent Tumor in Patients with Treated Glioblastoma. Am J Roentgenol 210(1):1-6, 2017 DOI10.2214/AJR.17.18003.

 

Weller M1, Butowski N2, Tran DD3, Recht LD4, Lim M5, Hirte H6, Ashby L7, Mechtler L8, Goldlust SA9,    Iwamoto F10, Drappatz J11, O'Rourke DM12, Wong M13, Hamilton MG14, Finocchiaro G15, Perry J16, Wick W17, Green J18, He Y18, Turner CD18, Yellin MJ18, Keler T18, Davis TA18, Stupp R19, Sampson JH20; ACT IV trial investigators.    Rindopepimut with temozolomide for patients with newly diagnosed, EGFRvIII-expressing glioblastoma (ACT IV): A randomised, double-blind, international phase 3 trial. Lancet Oncol. 2017 Oct; 18(10):1373-1385. doi: 10.1016/S1470-2045(17)30517-X. Epub 2017 Aug 23 PMID: 28844499

 

Goyal U, Suszko J Stea, B. The feasibility of using ultrasound during follow-up for superficial non-melanoma skin cancers after electronic brachytherapy. J. Contemporary Brachytherapy, 2017, Vol 9, number  6

 

Knitter JR; Erly WK; Stea B; Lemole GM; Germano IM; Doshi AH; Nael K. Interval Change in DWI and     Perfusion MRI Parameters for the Assessment of Pseudoprogression in Cerebral Metastases Treated with Stereotactic Radiation. In press AJR  April 2018

 

Emmanuel Katsanis, E, Sapp LN, Varner N, Koza S, Stea B, Zeng, Y. Excellent disease-free survival in pediatric and young adult patients with hematologic malignancies following haploidentical bone marrow transplantation and post-transplant cyclophosphamide-bendamustine. Biology of Blood and Marrow Transplantation; May 2018; DOI: https://doi.org/10.1016/j.bbmt.2018.06.007

 

Stea B, Skrepnik T, Hsu CC, Abendroth R. The Role of Radiation Therapy in the Treatment of Metastatic Cancer, to Clinical & Experimental Metastasis. Accepted: Clinical and Experimental Metastasis. July 2018;   https://doi.org/10.1007/s10585-018-9926-6 

 

Samuel Kim, MD, David A. Bull, MD, Linda Garland, MD, Zain Khalpey, MD PhD, Baldasarre Stea, MD PhD, Sun Yi, MD, Charles C. Hsu MD PhD. Is There a Role for Surgical Resection in Early Stage Sarcomatoid or Biphasic Mesothelioma? Results of a Propensity Score Matched Analysis. Annals of Thoracic Surgery (accepted, in press)
 

Clinical Studies

Titlesort descending Description Cancer Area Cancer Type Trial Status
CCTG CE.7

NCT03550391: Phase III Trial of Stereotactic Radiosurgery Compared with Whole Brain Radiotherapy (WBRT) for 5-15 Brain Metastases

NRG-BN003

NCT03180268: Phase III Trial of Observation Versus Irradiation for a Gross Totally Resected Grade II Meningioma