Shona T. Dougherty, MB, ChB, PhD
Office Location: 3838 N Campbell Ave, BLDG 2
Dr. Dougherty earned her medical degree from the University of Edinburgh, Edinburgh, Scotland in 1985, and her doctorate from the University of British Columbia, Vancouver, British Columbia, Canada in 1995. She was assistant professor at UCLA from 1996-2003, where she supervised the prostate seed brachytherapy program, as well as the TBI (total body irradiation) service. Dr. Dougherty joined the Arizona Cancer Center in August 2003, and has since been a zealous educator, directing the Radiation Oncology Residency Training Program since 2004.
Dr. Dougherty specializes in prostate cancer, and as an expert in prostate brachytherapy, presides over the prostate seed implant program at UAHN. Her primary interests include genitourinary cancers such as prostate, bladder and kidney disease. Additionally, she focuses on radiotherapy for gynecologic cancers, including various applications of brachytherapy. As a research scientist, Dr. Dougherty is currently involved in database construction to assess retrospective prostate radiotherapy outcomes. Dr. Dougherty became the departmental clinic director in 2003, and joined Dr. Baldassarre Stea (head of Radiation Oncology) as associate head of the department in 2008. She serves on several committees throughout the organization overseeing physician credentialing, resident education, quality assurance and program development.
Degrees
- Doctorate: University of British Columbia, Vancouver, British Columbia, Canada
- Fellowship: Royal College of Physicians and Surgeons of Canada
- Medical School: University of Edinburgh, Edinburgh, Scotland
- Undergraduate School: University of Edinburgh, Edinburgh, Scotland
Awards
- Distinction Award-Psychiatry, University of Edinburgh, Scotland
- Distinction Award-Community Medicine, University of Edinburgh, Scotland
- Selected to attend the Sixth National Cancer Institute of Canada Course in Oncology, McMaster University, Hamilton, Ontario, Canada
- National Cancer Institute of Canada Fellowship Award
- Canadian Association of Radiation Oncologists Residents Research Award (1992)
- Canadian Association of Radiation Oncologists Residents Research Award (1993)
- Listed in "The Best Doctors in America," 2009
Licensure & Certification
- Board eligible for Radiation Oncology Fellow of the Royal College of Physicians and Surgeons of Canada
- USMLE I USMLE II LMCC (Licentiate of the Medical Council of Canada)
- CSA (Clinical Skills Assessment)
- ECFMG Certificate
Research Interests
Selected Publications:
Hayes, G.M., Dougherty, S.T., Davis, P.D. and Dougherty, G.J. Molecular mechanisms regulating the tumor targeting potential of splice-activated gene expression. Cancer Gene Therapy 11:797-807, 2004.
Dougherty, S.T., Davis, P.D. and Dougherty, G.J. Vascular-targeted cancer gene therapy. Expert Opinion in Biology Therapy 4(12):1911-1920, 2004.
Dougherty, G.J., Davis, P.D. and Dougherty, S.T. Development of vascular targeted cancer gene therapy. In: Vascular Targeted Therapies in Oncology, Siemann, D. (Ed). Chapter 14, p 247-259, John Wiley and Sons, Inc., New York, 2006.
Pawar, S.C., Dougherty, S., Pennington, M.E., Demetriou, M.C., Stea, B.D., Dorr, R.T. and Cress, A. Alpha 6 integrin Cleavage: Sensitizing human prostate cancer to ionizing radiation. International Journal of Radiation Biology 83(11):761-767, 2007.
Dougherty, G.J. and Dougherty, S.T. Exploiting the tumor microenvironment in the development of targeted cancer gene therapy. Cancer Gene Therapy 16(3) 279-290, 2009.
Dougherty, S.T., Walker, S., Davis, P.D. and Dougherty, G.J. The novel vascular disrupting agent ANG501 induces cell cycle arrest and enhances endothelial cell sensitivity to radiation. Cancer Growth and Metastasis 2: 1-10, 2009.
Dougherty, S.T. and Dougherty, G.J. A cancer gene therapy approach that targets tumor-associated hyaluronan. Cancer Growth and Metastasis 2: 29-43, 2009.
Dougherty, G.J. and Dougherty, S.T. Vascular-targeted cancer gene therapy. In: ‘The Tumor Microenvironment’ Dietmar W. Siemann (Ed.) 401-419, John Wiley and Sons, Inc., New York. 2011.
Dougherty, S.T. and Dougherty, G.J. Mechanisms conferring resistance to pro-apoptotic cancer gene therapy. Journal of Cell Death 4: 19-30, 2011.
Skrepnik, T. and Dougherty, S. Principles of radiation therapy for uterine cancers. In: “Multidisciplinary Approach to Cancer of the Uterine Corpus” Odunsi (Ed.) Chapter 10, p67-72, 2013